HEY1_MOUSE Q9WV93
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UniProt:Q9WV93
Recommended name：Hairy/enhancer-of-split related with YRPW motif protein 1
EC number：
Alternative names：(Hairy and enhancer of split-related protein 1) (HESR-1) (Hairy-related transcription factor 1) (HRT-1) (mHRT1)
Cleaved into：
GeneID：
Gene names (primary )：Hey1
Gene names (synonym )：Herp2 Hesr1 Hrt1
Gene names (ORF )：
Length：299
Mass：32063
Sequence：MKRAHPDYSSSDSELDETIEVEKESADENGNLSSALCSMSPTTSSQVLARKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGSAKLEKAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLLVRLVSHLNNYASQREAASGAHGGLGHIPWGSAFGHHPHIAHPLLLPQNGHGNAGTAASPTEPHHQGRLASAHPEAPALRAPPSGGLGPVLPVVTSASKLSPPLLSSVASLSAFPFSFSSFHLLSPSTPTQAANLGKPYRPWGTEIGAF
Tissue specificity：Expressed in somitic mesoderm, brain, central nervous system, kidney, heart, nasal epithelium, limbs, lung, muscle, ovary and testis. {ECO:0000269|PubMed:10860664, ECO:0000269|PubMed:12947105}.
Induction：By activation of the Notch signaling pathway. {ECO:0000269|PubMed:10964718, ECO:0000269|PubMed:11095750, ECO:0000269|PubMed:11486044, ECO:0000269|PubMed:11741889}.
Developmental stage：Expressed in the developing nervous system, the somites, heart and craniofacial region. Expressed in the myocardium of the atrium at 9.5 dpc and in the atrioventricular cushions from 9.5 dpc to 12.5 dpc. Also expressed in developing and adult retina. Expressed in the ventricular zone of the ventral spinal cord at 12 dpc and in the ventricular zone of the telencephalon at 12 dpc and 15 dpc. Weakly expressed in the cortical plate at 15 dpc. {ECO:0000269|PubMed:10415358, ECO:0000269|PubMed:11160397, ECO:0000269|PubMed:12947105, ECO:0000269|PubMed:17259303, ECO:0000269|PubMed:17303760}.
Protein families：HEY family