NEUR4_MOUSE Q8BZL1
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UniProt:Q8BZL1
Recommended name：Sialidase-4
EC number：EC 3.2.1.18
Alternative names：(N-acetyl-alpha-neuraminidase 4) (Neuraminidase 4)
Cleaved into：
GeneID：241159
Gene names (primary )：Neu4
Gene names (synonym )：
Gene names (ORF )：
Length：478
Mass：52426
Sequence：MGPTRVPRRTVLFQRERTGLTYRVPALLCVPPRPTLLAFAEQRLSPDDSHAHRLVLRRGTLTRGSVRWGTLSVLETAVLEEHRSMNPCPVLDEHSGTIFLFFIAVLGHTPEAVQIATGKNAARLCCVTSCDAGLTWGSVRDLTEEAIGAALQDWATFAVGPGHGVQLRSGRLLVPAYTYHVDRRECFGKICWTSPHSLAFYSDDHGISWHCGGLVPNLRSGECQLAAVDGDFLYCNARSPLGNRVQALSADEGTSFLPGELVPTLAETARGCQGSIVGFLAPPSIEPQDDRWTGSPRNTPHSPCFNLRVQESSGEGARGLLERWMPRLPLCYPQSRSPENHGLEPGSDGDKTSWTPECPMSSDSMLQSPTWLLYSHPAGRRARLHMGIYLSRSPLDPHSWTEPWVIYEGPSGYSDLAFLGPMPGASLVFACLFESGTRTSYEDISFCLFSLADVLENVPTGLEMLSLRDKAQGHCWPS
Tissue specificity：Highly expressed in brain, particularly in hippocampus, and at lower levels in liver and spleen. Expressed in hippocampal neurons (at protein level). {ECO:0000269|PubMed:14637003, ECO:0000269|PubMed:19506080, ECO:0000269|PubMed:22393058}.
Induction：Down-regulated upon neuron differentiation. {ECO:0000269|PubMed:22393058}.
Developmental stage：Expressed at low levels in embryonic brain, then rapidly up-regulated after birth reaching a maximum at postnatal day 14, followed by a decrease. {ECO:0000269|PubMed:19506080}.
Protein families：Glycosyl hydrolase 33 family