NEPN_MOUSE Q9CQ76
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UniProt:Q9CQ76
Recommended name：Nephrocan
EC number：
Alternative names：
Cleaved into：
GeneID：66650
Gene names (primary )：Nepn
Gene names (synonym )：
Gene names (ORF )：
Length：512
Mass：57705
Sequence：MHPLWAFLLGLSLTNGLSANCPGRCSCDSMQSVQCYRLMELPSGIPSTTKRLYISHSRIQHLQLSNFTGLLALEDFILLASGTESIENDTFKTLSTLKTLELWKNKLRQVPSALPANLEVLKLNDNAICALRGSEFEGLKNLKVLELKNNLISSLSPSMLSPLASLQSLMVDGNNIESVVGPLSLPHLKYMSMENNQLHLIPGNVFTSLQNLQFLSFSGNFLTKIPINLPKSLLSLKMERNQLKVVRFRDMKHLENLSHLYLSENFLSSIDGAQQLTNLTTLEVSQNQLQMLPPRLPSRLQKLDCSSNFIQRVTAPEFQDLRDLKHLFLDNNVVSLFEAGALQRCSQLSNLALEQNLLLSIPLRLPKTLARLDLKGNAIQDMAERELRDLKQLQVLNLRNNRISALDFKALEGLPRLRHLYLDGNPWNCTCSLLRAREVLKAKGTDVKGGQCAAPAERQGESWMSSKKILRQCEHHLQQSEKSKETKKKPKPEDSSSIRLNMDDDDDDYEID
Tissue specificity：Expressed at highest levels in the kidney, where it is primarily detected in the epithelial cells of distal tubules and collecting ducts, and more weakly in proximal epithelial cells. Expressed at lower levels in heart and lung (at protein level). Detected in skeletal muscle. {ECO:0000269|PubMed:16990280}.
Induction：
Developmental stage：Detected in the definitive endoderm from 7.5 dpc onwards (PubMed:17683524). Strongly expressed in the developing midgut by 9 dpc, but then at 9.5 dpc expression appears to decrease (PubMed:17683524). Global expression levels peak during 11 dpc: also detected at slightly lower levels during 7 dpc, 15 dpc and 17 dpc (PubMed:16990280). {ECO:0000269|PubMed:16990280, ECO:0000269|PubMed:17683524}.
Protein families：Small leucine-rich proteoglycan (SLRP) family