FLCN_MOUSE Q8QZS3
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UniProt:Q8QZS3
Recommended name：Folliculin
EC number：
Alternative names：(Birt-Hogg-Dube syndrome protein homolog)
Cleaved into：
GeneID：216805
Gene names (primary )：Flcn
Gene names (synonym )：Bhd
Gene names (ORF )：
Length：579
Mass：64327
Sequence：MNAIVALCHFCELHGPRTLFCTEVLHAPLPQGAGSGDSPDQVEQAEEEEGGIQMSSRVRAHSPAEGASSESSSPGPKKSDMCEGCRSLAVGHPGYISHDKETSIKYVSHQHPNHPQLFSIVRQACVRSLSCEVCPGREGPIFFGDEQHGFVFSHTFFIKDSLARGFQRWYSIIAIMMDRIYLINSWPFLLGRIRGIISELQAKAFKVFEAEQFGCPQRAQRMNTAFTPFLHQRNGNAARSLTSLTSDDNLWACLHTSFAWLLKACGSRLTEKLLEGAPTEDTLVQMEKLADLEEESESWDNSEAEEEEKAPVTPEGAEGRELTSCPTESSFLSACGSWQPPKLTGFKSLRHMRQVLGAPSFRMLAWHVLMGNQVIWKSRDVNLVHSAFEVLRTMLPVGCVRIIPYSSQYEEAYRCNFLGLSPPVPIPAHVLASEFVVVVEVHTATRSNLHPAGCEDDQSLSKYEFVVTSGSPVAADRVGPTILNKIEAALTNQNLSVDVVDQCLICLKEEWMNKVKVLFKFTKVDSRPKEDTQKLLSVLGASEEDNVKLLKFWMTGLSKTYKSHLMSTVRSPTATESRS
Tissue specificity：Highly expressed in adult heart, pancreas, and prostate with moderate expression in adult brain, kidney, liver, adipose tissue and lung. {ECO:0000269|PubMed:19850877, ECO:0000269|PubMed:27913603}.
Induction：
Developmental stage：Expressed throughout embryogenesis (PubMed:19850877). At E5.5, expression is restricted to extraembryonic tissues; by E6.5, expressed in both embryonic and extraembryonic tissues (PubMed:19850877). Strong expression is observed in certain tissues including neural ectoderm, headfold and limb buds, while it is weakly expressed in the surrounding endoderm and heart (PubMed:19850877). {ECO:0000269|PubMed:19850877}.
Protein families：Folliculin family