EMB_MOUSE P21995
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UniProt:P21995
Recommended name:Embigin
EC number:
Alternative names:(Teratocarcinoma glycoprotein Gp-70)
Cleaved into:
GeneID:13723
Gene names (primary ):Emb
Gene names (synonym ):Gp70
Gene names (ORF ):
Length:330
Mass:37064
Sequence:MRSHTGLRALVAPGYPLLLLCLLAATRPDPAEGDPTDPTFTSLPVREEMMAKYSNLSLKSCNISVTEKSNVSVEENVILEKPSHVELKCVYTATKDLNLMNVTWKKDDEPLETTGDFNTTKMGNTLTSQYRFIVFNSKQLGKYSCVFGEKELRGTFNIHVPKAHGKKKSLIAYVGDSTVLKCVCQDCLPLNWTWYMGNETAQVPIDAHSNEKYIINGSHANETRLKIKHLLEEDGGSYWCRATFQLGESEEQNELVVLSFLVPLKPFLAILAEVILLVAIILLCEVYTHKKKNDPDAGKEFEQIEQLKSDDSNGIENNVPRYRKTDSADQ
Tissue specificity:Only member of the immunoglobulin superfamily to be expressed in embryonal carcinoma cells, which resemble multipotential cells of early embryos. {ECO:0000269|PubMed:2963822}.
Induction:Regulated by muscle activity. Strongly up-regulated after muscle denervation, including that of gastrocnemius muscle. Maximal expression is observed 10 days after denervation (at protein level). {ECO:0000269|PubMed:19164284}.
Developmental stage:At neuromuscular junctions, 5-fold higher expression levels at P0 compared to adult. {ECO:0000269|PubMed:19164284}.
Protein families: