DUS15_MOUSE Q8R4V2
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UniProt:Q8R4V2
Recommended name：Dual specificity protein phosphatase 15
EC number：EC 3.1.3.16
Alternative names：(Dual specificity protein phosphatase T-DSP10)
Cleaved into：
GeneID：252864
Gene names (primary )：Dusp15
Gene names (synonym )：
Gene names (ORF )：
Length：235
Mass：26186
Sequence：MGNGMTKVLPGLYLGNFIDAKDPDQLGRNKITHIISIHESPQPLLQDITYLRISVSDTPEVPIKKHFKECVHFIHSCRLNGGNCLVHCFAGISRSTTIVIAYVMTVTGLGWQEVLEAIKASRPIANPNPGFRQQLEEFGWANSQKLRRQLEERFGEIPFRDEEDLRALLPLCRRCRQGSATSAASATTASSAAEGTLQRLVPRSPRDSHQPLPLLARVKQTFFCLPRCLSRKGGK
Tissue specificity：Isoform 1 is expressed in testis; predominantly in developing spermatocytes (at protein level) (PubMed:15138252). Isoform 2 is highly expressed in testis (PubMed:11432789). Expressed in spinal chord and specifically in oligodendroglial cells (PubMed:27532821). Expressed in embryonic brain cortex; down-regulated in mice with experimental autoimmune encephalomyelitis (EAE) (PubMed:22792334). {ECO:0000269|PubMed:11432789, ECO:0000269|PubMed:22792334, ECO:0000269|PubMed:27532821}.
Induction：Down-regulated by nerve injury. {ECO:0000269|PubMed:22792334}.
Developmental stage：Expression increases during oligodendrocyte differentiation. Detected in spinal chord in late fetal (18.5 dpc) and early postnatal (P3 and P7) stages. Expression decreases in later postnatal development (P14 and P30). {ECO:0000269|PubMed:22792334, ECO:0000269|PubMed:27532821}.
Protein families：Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily