BSND_RAT Q8R2H3
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UniProt:Q8R2H3
Recommended name:Barttin
EC number:
Alternative names:
Cleaved into:
GeneID:192675
Gene names (primary ):Bsnd
Gene names (synonym ):
Gene names (ORF ):
Length:308
Mass:33,895
Sequence:MADEKTFRIGFIVLGLFLLSLGTFLMSHDRPQVYGTFYAMGSIMVIGGVLWSMCQCYPKITFVPADSDFQGMLSPKALSLLETGLSEVKSPQPPYVRLWEEAAYDQSLPDFTHIQMKVMGYSEDPRPLLAPELKTGTSSAKEGEPHSAQTWMEAAVVVHRELDEKEGEKSRSQSSPPACSQGSAPLASFHDDLDVGSSEGRSPQPSPPDRDEAHLQVPWASRGPLDRFGDFALIDDTPISEDMGLEGQAQEEALPSKQPWSLRMKEETVQAGAEEPEQEEEDLYYGLPDSPGDPLPDKELGFEPDVQG
Tissue specificity:Expressed along the distal nephron. 1
Induction:
Developmental stage:Regulated in parallel with CLCNKA under furosemide treatment. A significant decrease occurred after furosemide treatment in inner medulla (0.5 fold), whereas cortical and outer medulla levels remained unaffected. Regulation with CLCNKA in inner medulla is limited to the thin limb; levels in collecting ducts were not affected by furosemide treatment. During furosemide treatment selective down-regulation with CLCNKA in thin limb plays a role in maintaining salt and water homeostasis. 1
Protein families: