SIR6_MOUSE P59941
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UniProt:P59941
Recommended name：NAD-dependent protein deacetylase sirtuin-6
EC number：EC 2.3.1.286
Alternative names：(Regulatory protein SIR2 homolog 6) (SIR2-like protein 6)
Cleaved into：
GeneID：50721
Gene names (primary )：Sirt6
Gene names (synonym )：Sir2l6
Gene names (ORF )：
Length：334
Mass：36920
Sequence：MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLMWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFENARPSKTHMALVQLERMGFLSFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECPKCKTQYVRDTVVGTMGLKATGRLCTVAKTRGLRACRGELRDTILDWEDSLPDRDLMLADEASRTADLSVTLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRQADLRIHGYVDEVMCRLMKHLGLEIPAWDGPCVLDKALPPLPRPVALKAEPPVHLNGAVHVSYKSKPNSPILHRPPKRVKTEAAPS
Tissue specificity：Highest levels are found in muscle, thymus, spleen, brain and heart (at protein level). {ECO:0000269|PubMed:15795229, ECO:0000269|PubMed:16439206}.
Induction：
Developmental stage：Expression peaks at embryonic day 11 and persists into adulthood. {ECO:0000269|PubMed:15795229}.
Protein families：Sirtuin family, Class IV subfamily