MGAT3_MOUSE Q10470
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UniProt:Q10470
Recommended name：Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
EC number：EC 2.4.1.144
Alternative names：(N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III) (GNT-III) (GlcNAc-T III) (N-acetylglucosaminyltransferase III)
Cleaved into：
GeneID：
Gene names (primary )：Mgat3
Gene names (synonym )：
Gene names (ORF )：
Length：538
Mass：62003
Sequence：MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLISSFFWNNAPVTPQASPEPGDPDLLRTPLYSHSPLLQPLSPSKATEELHRVDFVLPEDTTEYFVRTKAGGVCFKPGTRMLEKPSPGRTEEKTEVSEGSSARGPARRPMRHVLSSRERLGSRGTRRKWVECVCLPGWHGPSCGVPTVVQYSNLPTKERLVPREVPRRVINAININHEFDLLDVRFHELGDVVDAFVVCDSNFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDGVSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLEVVSGCTMDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCSWCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRSLIRTGGWFDGTQQEYPPADPSEHMYAPKYLLKNYDQFRYLLENPYREPKSTVEGGRQNQGSDGRSSAVRGKLDTAEG
Tissue specificity：Highly expressed in brain and kidney and to a much lesser extent in stomach, heart, intestine, uterus, testis, ovary and lung. Not present in spleen, liver and muscle. In brain, expressed in neurons of hippocampus (PubMed:11986323). {ECO:0000269|PubMed:11986323}.
Induction：Expression is up-regulated by CDH1/E-cadherin-mediated cell-cell interaction. {ECO:0000269|PubMed:16537539}.
Developmental stage：Expressed in brain at 10.5 dpc and thereafter. {ECO:0000269|PubMed:11986323}.
Protein families：Glycosyltransferase 17 family