SCD4_MOUSE Q6T707
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UniProt:Q6T707
Recommended name:Stearoyl-CoA desaturase 4
EC number:EC 1.14.19.1
Alternative names:(Acyl-CoA desaturase 4) (Delta(9)-desaturase 4) (Delta-9 desaturase 4) (Fatty acid desaturase 4)
Cleaved into:
GeneID:329065
Gene names (primary ):Scd4
Gene names (synonym ):
Gene names (ORF ):
Length:353
Mass:41042
Sequence:MTAHLPQEISSRCSTTNIMEPHSRRQQDGEEKMPLQAEDIRPEIKDDLYDPSYQDEEGPPPKLEYVWRNIIFMALLHVGALYGITLVPSCKVYTWLLGVFYNVVAGLGITAGAHRLWSHRTYKARLPLRIFLIMANTMAFQNDVYEWARDHRAHHKFSETHADPHNSRRGFFFSHVGWLLVRKHPAVKEKGKNLDMSDLKAEKLVMFQRRYYKLAVTLMFIILPTLVPWYLWGETFQHSLCVSNFLRYAVLLNFTWLVNSAAHLYGYRPYDRGIGARENPFVSMASLGEGFHNYHHTFPYDYSVSEYRWHINFTTFFIDCMAALGLAYDRKKVSKAVVLARIKRTGDGSHKSS
Tissue specificity:Detected in heart, but not in brain, liver, skin or adipose tissue. {ECO:0000269|PubMed:12815040}.
Induction:Up-regulated by agonists that activate NR1H3. Up-regulated by a fat-free high-carbohydrate diet. Not down-regulated by a high-carbohydrate diet supplemented with unsaturated fatty acids. Down-regulated by leptin. {ECO:0000269|PubMed:12815040}.
Developmental stage:
Protein families:Fatty acid desaturase type 1 family