CD36_MOUSE Q08857
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UniProt:Q08857
Recommended name:Platelet glycoprotein 4
EC number:
Alternative names:(Glycoprotein IIIb) (GPIIIB) (PAS IV) (PAS-4) (Platelet glycoprotein IV) (GPIV) (CD antigen CD36)
Cleaved into:
GeneID:12491
Gene names (primary ):Cd36
Gene names (synonym ):
Gene names (ORF ):
Length:472
Mass:52698
Sequence:MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDMLIEKTIKREVVLEEGTTAFKNWVKTGTTVYRQFWIFDVQNPDDVAKNSSKIKVKQRGPYTYRVRYLAKENITQDPEDHTVSFVQPNGAIFEPSLSVGTEDDNFTVLNLAVAAAPHIYQNSFVQVVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVPYPISTTVGVFYPYNDTVDGVYKVFNGKDNISKVAIIESYKGKRNLSYWPSYCDMINGTDAASFPPFVEKSRTLRFFSSDICRSIYAVFGSEIDLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLHPNEDEHRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFKTQVTGKIKLLGMVEMALLGIGVVMFVAFMISYCACKSKNGK
Tissue specificity:Expressed in the apical side of lingual taste bud cells of the circumvallate papillae (PubMed:16276419, PubMed:21901153). Highly expressed in the intestine on the luminal surface of enterocytes. In small intestines expression levels follow a steep decreasing gradient from proximal to distal segments (PubMed:17507371). Expressed in macrophages (PubMed:23395392, PubMed:23812099). Cell surface expression detected in lung alveolar macrophages, dendritic macrophages and lung macrophages (at protein level) (PubMed:19362712). {ECO:0000269|PubMed:16276419, ECO:0000269|PubMed:17507371, ECO:0000269|PubMed:19362712, ECO:0000269|PubMed:21901153, ECO:0000269|PubMed:23395392, ECO:0000269|PubMed:23812099}.
Induction:Expressed in a circadian manner in the circumvallate papillae, levels being lower during the dark period. Protein levels decrease in presence of lipids. {ECO:0000269|PubMed:21901153}.
Developmental stage:
Protein families:CD36 family