FZD3_MOUSE Q61086
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q61086
Recommended name：Frizzled-3
EC number：
Alternative names：(Fz-3) (mFz3)
Cleaved into：
GeneID：14365
Gene names (primary )：Fzd3
Gene names (synonym )：
Gene names (ORF )：
Length：666
Mass：76208
Sequence：MAVSWIVFDLWLLTVFLGQIGGHSLFSCEPITLRMCQDLPYNTTFMPNLLNHYDQQTAALAMEPFHPMVNLDCSRDFRPFLCALYAPICMEYGRVTLPCRRLCQRAYSECSKLMEMFGVPWPEDMECSRFPDCDEPYPRLVDLNLVGDPTEGAPVAVQRDYGFWCPRELKIDPDLGYSFLHVRDCSPPCPNMYFRREELSFARYFIGLISIICLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDRVACNASSPAQYKASTVTQGSHNKACTMLFMVLYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQMSRPDLILFLMKYLMALIVGIPSIFWVGSKKTCFEWASFFHGRRKKEIVNESRQVLQEPDFAQSLLRDPNTPIIRKSRGTSTQGTSTHASSTQLAMVDDQRSKAGSVHSKVSSYHGSLHRSRDGRYTPCSYRGMEERLPHGSMSRLTDHSRHSSSHRLNEQSRHSSIRDLSNNPMTHITHGTSMNRVIEEDGTSA
Tissue specificity：Expressed in the cortex, diencephalon, rostral brainstem and little or no staining is seen in the striatum or cerebellum. Expressed in both hair cells and supporting cells in the utricle, saccule, cristae and the organ of Corti in the inner ear (at protein level). Highly expressed in the CNS. In skin, it is restricted to the epidermis and to the developing hair follicle. {ECO:0000269|PubMed:11407985, ECO:0000269|PubMed:12351730, ECO:0000269|PubMed:16495441, ECO:0000269|PubMed:8626800}.
Induction：
Developmental stage：Expressed throughout the developing central nervous system (CNS). Expressed in the cortex, diencephalon, and brainstem, with the most intense staining in the striatum and trigeminal ganglia at 18 dpc (at protein level). First detected in discrete foci in the developing epidermis of 13 days old embryos, later in the hair follicle placodes of 15 days old embryos. Expressed in the ventral and lateral margins of the spinal cord from 9.5 to 13.5 dpc, where post-crossing commissural axons project longitudinally. Expressed in superior sympathetic cervical ganglia (SCG) at 14.5 and 16.5 dpc, a stage when the SCG is comprised primarily of proliferating sympathetic neuroblasts. In 17 days embryos and 1 day old newborn, expression is limited to suprabasal keratinocytes and is not seen in pelage follicles until 3 days postpartum. In 7 days old neonatal skin, expression occurs throughout the epidermis and in the outer cell layers of hair follicles. {ECO:0000269|PubMed:11407985, ECO:0000269|PubMed:12351730, ECO:0000269|PubMed:14671310, ECO:0000269|PubMed:21325504}.
Protein families：G-protein coupled receptor Fz/Smo family