CLC2D_MOUSE   Q91V08


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UniProt:Q91V08

Recommended name:C-type lectin domain family 2 member D

EC number:

Alternative names:(C-type lectin-related protein B) (Clr-b) (Lectin-like transmembrane protein) (Osteoclast inhibitory lectin)

Cleaved into:

GeneID:93694

Gene names  (primary ):Clec2d

Gene names  (synonym ):Clrb Ocil

Gene names  (ORF ):

Length:207

Mass:23647

Sequence:MCVTKASLPMLSPTGSPQEVEVGKILQGKRHGTISPESCAKLYCYYGVIMVLTVAVIALSVALSATKTEQIPVNKTYAACPQNWIGVENKCFYFSEYPSNWTFAQAFCMAQEAQLARFDNQDELNFLMRYKANFDSWIGLHRESSEHPWKWTDNTEYNNTIPIRGEERFAYLNNNGISSTRIYSLRMWICSKLNSYSLHCQTPFFPS

Tissue specificity:Detected in fetal heart, brain, lung, chondrocytes, perichondrium and osteoblasts, and in adult splenocytes, thymocytes, lymph-node cells, osteoblasts, growth plate chondrocytes and skeletal muscle overlying the bone (at protein level). Ubiquitous. Detected in thymus, bone marrow, lung, gut, heart, skeletal muscle, ovary, spleen, ileum, liver and kidney. {ECO:0000269|PubMed:11278931, ECO:0000269|PubMed:11398965, ECO:0000269|PubMed:12374791, ECO:0000269|PubMed:14990792, ECO:0000269|PubMed:16751398}.

Induction:Constitutively expressed in bone marrow cells. Down-regulated by treatment with 1,25-dihydroxyvitamin D3. Up-regulated in calvarial osteoblast cells by IL-1alpha, IL11, and 1,25-dihydroxyvitamin D3. {ECO:0000269|PubMed:11278931}.

Developmental stage:

Protein families:


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