CLC2D_MOUSE Q91V08
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q91V08
Recommended name:C-type lectin domain family 2 member D
EC number:
Alternative names:(C-type lectin-related protein B) (Clr-b) (Lectin-like transmembrane protein) (Osteoclast inhibitory lectin)
Cleaved into:
GeneID:93694
Gene names (primary ):Clec2d
Gene names (synonym ):Clrb Ocil
Gene names (ORF ):
Length:207
Mass:23647
Sequence:MCVTKASLPMLSPTGSPQEVEVGKILQGKRHGTISPESCAKLYCYYGVIMVLTVAVIALSVALSATKTEQIPVNKTYAACPQNWIGVENKCFYFSEYPSNWTFAQAFCMAQEAQLARFDNQDELNFLMRYKANFDSWIGLHRESSEHPWKWTDNTEYNNTIPIRGEERFAYLNNNGISSTRIYSLRMWICSKLNSYSLHCQTPFFPS
Tissue specificity:Detected in fetal heart, brain, lung, chondrocytes, perichondrium and osteoblasts, and in adult splenocytes, thymocytes, lymph-node cells, osteoblasts, growth plate chondrocytes and skeletal muscle overlying the bone (at protein level). Ubiquitous. Detected in thymus, bone marrow, lung, gut, heart, skeletal muscle, ovary, spleen, ileum, liver and kidney. {ECO:0000269|PubMed:11278931, ECO:0000269|PubMed:11398965, ECO:0000269|PubMed:12374791, ECO:0000269|PubMed:14990792, ECO:0000269|PubMed:16751398}.
Induction:Constitutively expressed in bone marrow cells. Down-regulated by treatment with 1,25-dihydroxyvitamin D3. Up-regulated in calvarial osteoblast cells by IL-1alpha, IL11, and 1,25-dihydroxyvitamin D3. {ECO:0000269|PubMed:11278931}.
Developmental stage:
Protein families: