AQP2_MOUSE P56402
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UniProt:P56402
Recommended name：Aquaporin-2
EC number：
Alternative names：(AQP-2) (ADH water channel) (Aquaporin-CD) (AQP-CD) (Collecting duct water channel protein) (WCH-CD) (Water channel protein for renal collecting duct)
Cleaved into：
GeneID：11827
Gene names (primary )：Aqp2
Gene names (synonym )：cph
Gene names (ORF )：
Length：271
Mass：28965
Sequence：MWELRSIAFSRAVLAEFLATLLFVFFGLGSALQWASSPPSVLQIAVAFGLGIGTLVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAGQAVTVELFLTMQLVLCIFASTDERRSDNLGSPALSIGFSVTLGHLLGIYFTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAVIGSLLYNYLLFPSTKSLQERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGSKA
Tissue specificity：Detected in principal cells in the collecting duct in kidney medulla and cortex (at protein level) (PubMed:10191086, PubMed:16641094, PubMed:31605441). Expressed in a radial pattern from the cortex through the outer medulla into the inner medulla (PubMed:12426236). Higher levels in the inner medulla (PubMed:12426236). {ECO:0000269|PubMed:10191086, ECO:0000269|PubMed:12426236, ECO:0000269|PubMed:16641094, ECO:0000269|PubMed:31605441}.
Induction：Increased levels on water deprivation. {ECO:0000269|PubMed:10191086}.
Developmental stage：
Protein families：MIP/aquaporin (TC 1.A.8) family