PRUN1_MOUSE Q8BIW1
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UniProt:Q8BIW1
Recommended name：Exopolyphosphatase PRUNE1
EC number：EC 3.6.1.1
Alternative names：(PRUNEM1)
Cleaved into：
GeneID：229589
Gene names (primary )：Prune1
Gene names (synonym )：Prune
Gene names (ORF )：
Length：454
Mass：50239
Sequence：MEDYLQDCRAALQDSRPLHVVLGNEACDLDSMVSALALAFYLTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIPEPALIFRDEIDLLALHQAGQLTLILVDHHILPKSDAALEEAVAEVLDHRPIEQKYCPPCHVSVELVGSCATLVTERILQGAPETLDRQTAALLHGTIILDCVNMDTNIGKATPKDSKYVEELEALFPDLPKRKDIFDSLQKAKFDVSGLTTEQMLRKDQKTVYRQGTKVAISAIYMDLKAFLQRTDLFTDLSSFCHDHSYDALVAMTIFFNTQNEPVRQLAIFCPHEALRMTICGILERSTSPPLKLTPIPSTSPNLQAYHQGNTQVSRKKLLPVLQEALSAYLDSAKMASGQSEVAVGMSREQVDKDLDKASNSLISGLSQDEEDPPLPPTPMNSLVDECPLDQGLPKFSAEAVFEKCSQISLSQSARACTSNK
Tissue specificity：
Induction：
Developmental stage：In the developing embryo, a high level of expression is confined to the nervous system particularly in the dorsal root ganglia, cranial nerves, and neural retina. From 10.5 dpc, expressed at low levels in the basal plate along the entire neural tube, while at 12.5 dpc the expression in the nervous system is definitively stronger, especially in the cranial and dorsal root ganglia and in the spinal nerves. In the hypothalamus, the expression is confined to the retro-chiasmatic area (RCH) and is also detectable in the remnant of the Rathke's pouch. In the developing eye, exclusively expressed in the prospective neural retina, equally distributed in both the deep and superficial layers. At 16.5 dpc, expression is still detectable in the outer neuroblast layer of the neural retina. {ECO:0000269|PubMed:10602478}.
Protein families：PPase class C family, Prune subfamily