IRX5_MOUSE Q9JKQ4
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UniProt:Q9JKQ4
Recommended name：Iroquois-class homeodomain protein IRX-5
EC number：
Alternative names：(Homeodomain protein IRXB2) (Iroquois homeobox protein 5)
Cleaved into：
GeneID：54352
Gene names (primary )：Irx5
Gene names (synonym )：Irxb2
Gene names (ORF )：
Length：484
Mass：50755
Sequence：MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAAFSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPESGGAEQKATAGCERLQGPLSPAGKETEGSLSDSDFKESSSEGRHDELPRPPRAGESSPAGPATARLAEDAGPHYPASVPAPGPHPSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGSEGSPCPPCPGPMGGQTLGGSRASPAPAPARSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFGHLHGHPGPGPSPTAGPGSHFNGLNQTVLNRADVLAKDPKMLRSQSQLDLCKDSPYELKKGMSDI
Tissue specificity：Not expressed in the developing metanephric kidney or adult kidney.
Induction：
Developmental stage：In 9.5 dpc embryos, expressed in the rhombencephalon, metencephalon, and in the cephalic mesoderm surround the optic vesicle. By 12.5 dpc, expression continues in the mesenchyme and also begins in subsets of cells in the neuroretina, becoming expressed in the retinal inner neuroblast layers by 16.5 dpc. Expressed in developing bipolar cells during retinal development starting at postnatal day 5, and expressed in a subset of cone bipolar cells in the mature retina. Also expressed along the spinal cord, in the ventricular layer, in motor neurons and in the proximal limb buds during embryonic development. Expressed in the developing heart in the endocardium that lines the heart chambers. {ECO:0000269|PubMed:10704856, ECO:0000269|PubMed:10926765, ECO:0000269|PubMed:16182275}.
Protein families：TALE/IRO homeobox family