DUS1_MOUSE   P28563


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UniProt:P28563

Recommended name:Dual specificity protein phosphatase 1

EC number:EC 3.1.3.16

Alternative names:(Mitogen-activated protein kinase phosphatase 1) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP)

Cleaved into:

GeneID:19252

Gene names  (primary ):Dusp1

Gene names  (synonym ):3ch134 Mkp1 Ptpn10 Ptpn16

Gene names  (ORF ):

Length:367

Mass:39370

Sequence:MVMEVGILDAGGLRALLREGAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSASLDGAKRDGTLALAAGALCREARSTQVFFLQGGYEAFSASCPELCSKQSTPTGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILSFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKDAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHPTNSALNYLKSPITTSPSC

Tissue specificity:

Induction:Up-regulated by growth factors and mitogens. {ECO:0000269|PubMed:1741163, ECO:0000269|PubMed:8355678}.

Developmental stage:Expression in lung increases after birth. {ECO:0000269|PubMed:8355678}.

Protein families:Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily


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