UBE2K_MOUSE P61087
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UniProt:P61087
Recommended name:Ubiquitin-conjugating enzyme E2 K
EC number:EC 2.3.2.23
Alternative names:(E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Cleaved into:
GeneID:53323
Gene names (primary ):Ube2k
Gene names (synonym ):Hip2
Gene names (ORF ):
Length:200
Mass:22407
Sequence:MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN
Tissue specificity:Expressed in the brain, with highest levels found in the mitral cells of the olfactory bulb, the pyramidal cell layer of the hippocampus and the Purkinje cells of the cerebellar cortex. {ECO:0000269|PubMed:10585161}.
Induction:
Developmental stage:Expressed at all stages of brain development and increases significantly between postnatal days 7 and 14. {ECO:0000269|PubMed:10585161}.
Protein families:Ubiquitin-conjugating enzyme family