PGES2_MOUSE Q8BWM0
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UniProt:Q8BWM0
Recommended name：Prostaglandin E synthase 2
EC number：EC 5.3.99.3
Alternative names：(GATE-binding factor 1) (GBF-1) (Microsomal prostaglandin E synthase 2) (mPGES-2)
Cleaved into：Prostaglandin E synthase 2 truncated form
GeneID：96979
Gene names (primary )：Ptges2
Gene names (synonym )：Gbf1 Pges2
Gene names (ORF )：
Length：384
Mass：43324
Sequence：MAQAARLSWVLVSSRCALTEGLLTRPWQPLSAQSRAGFTRVAAGSRGAAVRKGSPRLLGAAALALGGALGLYHTVRWHQRSQDLRAERSAAQLPLSNSLQLTLYQYKTCPFCSKVRAFLDFHSLPYQVVEVNPVRRTEIKFSSYRKVPILVAQEGDSLQQLNDSSVIISALKTYLVSGQPLEEVITYYPPMKAMNDQGKEVTEFCNKYWLMLDEKEAQQMYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPAEALASFDYIVREGKFGAVEAAMAKYVGAAAMYLISKRLKSRHHLQDDVRVDLYEAANKWVTAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLEAFDDLMRHSHIQPWYLRMERAIEEAPSVHHVNPSCKD
Tissue specificity：Widely expressed. Expressed in brain, heart, liver, colon and lung. {ECO:0000269|PubMed:12050152, ECO:0000269|PubMed:12835322}.
Induction：Constitutively expressed. Not induced during tissue inflammation. Down-regulated in the absence of Ptges. {ECO:0000269|PubMed:12835322, ECO:0000269|PubMed:15584915}.
Developmental stage：
Protein families：GST superfamily