ANGL3_MOUSE Q9R182
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UniProt:Q9R182
Recommended name：Angiopoietin-related protein 3
EC number：
Alternative names：(Angiopoietin-like protein 3)
Cleaved into：ANGPTL3(17-224)
GeneID：30924
Gene names (primary )：Angptl3
Gene names (synonym )：
Gene names (ORF )：
Length：455
Mass：52543
Sequence：MHTIKLFLFVVPLVIASRVDPDLSSFDSAPSEPKSRFAMLDDVKILANGLLQLGHGLKDFVHKTKGQINDIFQKLNIFDQSFYDLSLRTNEIKEEEKELRRTTSTLQVKNEEVKNMSVELNSKLESLLEEKTALQHKVRALEEQLTNLILSPAGAQEHPEVTSLKSFVEQQDNSIRELLQSVEEQYKQLSQQHMQIKEIEKQLRKTGIQEPSENSLSSKSRAPRTTPPLQLNETENTEQDDLPADCSAVYNRGEHTSGVYTIKPRNSQGFNVYCDTQSGSPWTLIQHRKDGSQDFNETWENYEKGFGRLDGEFWLGLEKIYAIVQQSNYILRLELQDWKDSKHYVEYSFHLGSHETNYTLHVAEIAGNIPGALPEHTDLMFSTWNHRAKGQLYCPESYSGGWWWNDICGENNLNGKYNKPRTKSRPERRRGIYWRPQSRKLYAIKSSKMMLQPTT
Tissue specificity：Predominantly expressed in liver, weakly expressed in kidney and lung. Expressed in podocytes (at protein level). Expressed in hypothalamic neurons (at protein level). Expressed in bone marrow sinusoidal endothelial cells (at protein level). {ECO:0000269|PubMed:10644446, ECO:0000269|PubMed:20959605, ECO:0000269|PubMed:25338813, ECO:0000269|PubMed:25710887}.
Induction：Down-regulated by insulin and leptin. Not regulated by nutritional status (fed/fasting) Up-regulated in podocytes by puromycin. Up-regulated after feeding in the hypothalamus. {ECO:0000269|PubMed:15336575, ECO:0000269|PubMed:15863837, ECO:0000269|PubMed:20424482, ECO:0000269|PubMed:25338813}.
Developmental stage：
Protein families：