SPZ1_MOUSE   Q99MY0


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UniProt:Q99MY0

Recommended name:Spermatogenic leucine zipper protein 1

EC number:

Alternative names:(BHLH-Zip transcription factor SPZ1) (Spermatogenic Zip 1)

Cleaved into:

GeneID:79401

Gene names  (primary ):Spz1

Gene names  (synonym ):

Gene names  (ORF ):

Length:378

Mass:43091

Sequence:MSDTDNSAEMPARCPSPNPAPGAKQEPPNSGITISLLEIGSLPTVCYHSFPPPKNSICPVEKRGRVQKFSNLLKDVKDVLKNIAGVEEKSTVGEPFDDAYIPEDLSELNVRGVEKKNKIRFKDDLFIHFDPEREQNTMKQMLLKNQSAKNMVPKFARDLCNAEETRGFDGMLLSVKRPRNGSLHLRGEYRKLRNNMEQLLQEADHWSKQHNELSELMRSYQECQNETQETTDKDRACLQNQPNNGLSTKQKLEEQVKKLSHDTHALHLIAALLENECQVLQQRVDILKDFHLHEAGLGHEKPLQMSCEQDKKCPKLAEADKTDAFKHTTRATEGTIRKPKILRSPDVCFTKKARNNRFNARVAKKSLVGKRRTVSSFR

Tissue specificity:Expressed specifically in the testis and epidydimis. In the testis expressed in both germ cells and somatic cells (Sertoli and Leydig cells). Expressed in several tumor cell lines. {ECO:0000269|PubMed:11165476, ECO:0000269|PubMed:14980513, ECO:0000269|PubMed:15899793}.

Induction:Down-regulated by testosterone and retinoic acid. {ECO:0000269|PubMed:11165476}.

Developmental stage:First detected in the testis at postnatal day 10 and levels increase further and reach highest levels at day 40 and then gradually decrease. {ECO:0000269|PubMed:11165476}.

Protein families:


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