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CD83 molecular target information overview


  • Molecular name: CD83, CD83 molecule
  • Gene family: CD molecules; V-set domain containing
  • Alias: HB15; BL11
  • Alias: CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 molecule


    • CD83 molecular target review


    CD83, also known as HB15, has a molecular weight of 43 kD. It is a transmembrane protein that is weakly expressed in activated B cells, activated T cells, activated granulocytes, dendritic cells, and Langerhans cells. CD83 is a specific marker for dendritic cells and is involved in antigen presentation and lymphocyte activation. It can be used to identify and separate dendritic cells, follicular junction cells, and Langerhans cells in the blood.


    Human CD83 Molecular Target Information


    Molecular name: CD83, CD83 molecule


    Alias:

    • B-cell activation protein
    • BL11
    • CD83 antigen
    • CD83 antigen (activated B lymphocytes, immunoglobulin superfamily)
    • cell surface protein HB15
    • cell-surface glycoprotein
    • HB15
    • hCD83

    Gene sequence:NCBI_Gene: 9308

    Protein sequence: UniProtKB: Q01151


    Human CD83 target molecule function (prediction)


    Predicted to be involved in defense response; humoral immune response; and signal transduction. Predicted to act upstream of or within positive regulation of CD4-positive, alpha-beta T cell differentiation; regulation of cytokine production; and response to organic cyclic compound. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane.


    Mouse Cd83 molecular target information


    Molecular name: Cd83, CD83 antigen


    Alias:

    • None


    Gene sequence:NCBI_Gene: 12522

    Protein sequence:


    Mouse Mouse Cd83 Target Molecular Function (Prediction)


    Acts upstream of or within positive regulation of CD4-positive, alpha-beta T cell differentiation; regulation of cytokine production; and response to organic cyclic compound. Located in external side of plasma membrane. Is expressed in alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human CD83 (CD83 molecule).


    Rat Cd83 molecular target information


    Molecular name: Cd83, CD83 molecule

    Alias:

    • CD83 antigen
    • LOC361226

    Gene sequence:NCBI_Gene: 361226

    Protein sequence:UniProtKB: B2GV95


    Rat Cd83 target molecular function (prediction)


    Predicted to act upstream of or within positive regulation of CD4-positive, alpha-beta T cell differentiation; regulation of cytokine production; and response to organic cyclic compound. Predicted to be located in external side of plasma membrane. Orthologous to human CD83 (CD83 molecule).