NOE2_MOUSE Q8BM13
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UniProt:Q8BM13
Recommended name：Noelin-2
EC number：
Alternative names：(Olfactomedin-2)
Cleaved into：
GeneID：244723
Gene names (primary )：Olfm2
Gene names (synonym )：
Gene names (ORF )：
Length：448
Mass：50720
Sequence：MRKLRQTGTTIAGGQTLFQSPEEGWQLYTSAQAPDGKCVCTAVIPAQSTCARDGRSRELRQLMEKVQNVSQSMEVLELRTFRDLQYVRSMETLMRSLDARLRAADGSVSAKSFQELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGNLAAIQEEMGAYGYEDLQQRVMALEARLHACAQKLGCGKLTGVSNPITIRAMGSRFGSWMTDTMAPSADSRVWYMDGYYKGRRVLEFRTLGDFIKGQNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFPYSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVVRSWDTGYPKRSAGEAFMICGVLYVTNSHLAGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWNNGHQVLYNVTLFHVISTAGDP
Tissue specificity：Expressed in the brain (at protein level) (PubMed:22632720). In the developing eye, first detected at 12 dpc in the retinal pigmented epithelium and preferentially expressed in differentiating retinal ganglion cells between 15 and 18 dpc (PubMed:21228389). In the brain, expression is detected mainly in the olfactory bulb, cortex, piriform cortex, olfactory trabeculae, and inferior and superior colliculus (PubMed:25218043). In the adult eye, expression is detected mainly in retinal ganglion cells (PubMed:25218043). Expressed in carotid arteries (PubMed:28062493). {ECO:0000269|PubMed:21228389, ECO:0000269|PubMed:22632720, ECO:0000269|PubMed:25218043, ECO:0000269|PubMed:28062493}.
Induction：
Developmental stage：During embryonic eye development, first detected at 12 dpc with maximum levels at 19.5 dpc and down-regulation of expression postnatally. In brain, levels increase from 13.5 dpc to postnatal day 6 and decrease in the adult. {ECO:0000269|PubMed:21228389}.
Protein families：