APR_MOUSE Q9JM54
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UniProt:Q9JM54
Recommended name:Phorbol-12-myristate-13-acetate-induced protein 1
EC number:
Alternative names:(Protein Noxa)
Cleaved into:
GeneID:58801
Gene names (primary ):Pmaip1
Gene names (synonym ):Noxa
Gene names (ORF ):
Length:103
Mass:11566
Sequence:MPGRKARRNAPVNPTRAELPPEFAAQLRKIGDKVYCTWSAPDITVVLAQMPGKSQKSRMRSPSPTRVPADLKDECAQLRRIGDKVNLRQKLLNLISKLFNLVT
Tissue specificity:Detected in thymocytes after irradiation with X-rays. Not detectable in untreated thymocytes (at protein level). Detected in embryonic neural precursor cells of the telencephalon Constitutively expressed at low levels in adult brain, testis, thymus, spleen, lung and kidney. {ECO:0000269|PubMed:16822983}.
Induction:Up-regulated after exposure to ionizing radiation and other genotoxic agents. Up-regulation is mediated by p53. {ECO:0000269|PubMed:16822983}.
Developmental stage:
Protein families:PMAIP1 family