TBCB_MOUSE Q9D1E6
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UniProt:Q9D1E6
Recommended name:Tubulin-folding cofactor B
EC number:
Alternative names:(Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B)
Cleaved into:
GeneID:66411
Gene names (primary ):Tbcb
Gene names (synonym ):Ckap1
Gene names (ORF ):
Length:244
Mass:27386
Sequence:MEVTGISAPTVMVFISSSLNSFRSEKRYSRSLTIAEFKCKLELVVGSPASCMELELYGADDKFYSKLDQEDALLGSYPVDDGCRIHVIDHSGVRLGEYEDVSKVEKYEISPEAYERRQNTVRSFMKRSKLGPYNEELRAQQEAEAAQRLSEEKAQASAISVGSRCEVRAPDHSLRRGTVMYVGLTDFKPGYWVGVRYDEPLGKNDGSVNGKRYFECQAKYGAFVKPSAVTVGDFPEEDYGLDEM
Tissue specificity:Widely expressed with highest levels in brain. Broadly distributed throughout the neonate brain but restricted mainly to ependymary cells in the adult brain where it is concentrated in the cilia. {ECO:0000269|PubMed:17217416}.
Induction:
Developmental stage:In the embryo, expression increases at 12.5 dpc-14.5 dpc. Levels are highest in pre- and postnatal stages which coincide with peaks of cerebral and cerebellar neurogenesis (at protein level). {ECO:0000269|PubMed:17217416}.
Protein families:TBCB family