4F2_RAT   Q794F9


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UniProt:Q794F9

Recommended name:Amino acid transporter heavy chain SLC3A2 Curated

EC number:

Alternative names:CD98

Cleaved into:

GeneID:50567

Gene names  (primary ):Slc3a2

Gene names  (synonym ):

Gene names  (ORF ):

Length:527

Mass:58,072

Sequence:MSQDTEVDMKDVELNELEPEKQPMNAADGAAAGEKNGLVKIKVAEDEAEAGVKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPVQRWWHKGALYRIGDLQAFVGPEARGIAGLKNHLEYLSTLKVKGLVLGPIHKNQKDEVNETDLKQIDPDLGSQEDFKDLLQSAKKKSIHIILDLTPNYKGQNAWFLPPQADIVATKMKEALSSWLQDGVDGFQVRDVGKLANASLYLAEWQNITKNFSEDRLLIAGTASSDLQQIVNILESTSDLLLTSSYLSQPVFTGEHAELLVIKYLNATGSRWCSWSVSQAGLLTSFIPAQFLRLYQLLLFTLPGTPVFSYGDELGLQAVALPGQPMEAPFMLWNESSNSQTSSPVSLNMTVKGQNEDPGSLLTQFRRLSDLRGKERSLLHGDFDALSSSSGLFSYVRHWDQNERYLVVLNFQDVGLSARVGASNLPAGISLPASANLLLSTDSTRLSREEGTSLSLENLSLNPYEGLLLQFPFVA

Tissue specificity:In brain expressed on capillary endothelia in cerebral cortex (at protein level) (PubMed:11095508). Highest expression in kidney, jejunum, ileum, colon, placenta, testis and spleen. Lower levels found in liver, lung and brain with weakest expression in heart. Expressed in retina, inner blood-retinal barrier of retina, retinal vascular endothelial cells. Also expressed in C6 glioma cells and in the retinal capillary endothelial cell line TR-iBRB2 3 s

Induction:

Developmental stage:Expression induced in normal hepatic cells in the presence of actinomycin-D. 1

Protein families:


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