DAAM2_MOUSE Q80U19
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UniProt:Q80U19
Recommended name：Disheveled-associated activator of morphogenesis 2
EC number：
Alternative names：
Cleaved into：
GeneID：76441
Gene names (primary )：Daam2
Gene names (synonym )：Kiaa0381
Gene names (ORF )：
Length：1115
Mass：128370
Sequence：MALRKRSPHGLGFLCCFGGSDLPEIDLRDSHPLQYLEFSGPIPNPEELNVRFAELVDELDLTDKNREAVFALPPEKKWQIYCSKRKEQEDPNKLATSWPEYYIDRINAMAAMQNLYETEDEETDKRNQVVEDLKTALRTQPMRFVTRFIDLEGLTCLLNFLRGMDHTTCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISIIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQAYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMFELIHKKLKHTEAYPCLLSVLHHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGVDPDLAPLENFNVKNIVNMLINENEVKQWRDQAEKFRKEHMELMSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVARHNESSTGPVSSPPPPGGPLTLSSSRTTNDLPPPPPPLPFDSCPPPPAPPLPPGGPPIPPGAPPCFSSGPPPSHDPFSSNEAPLRKKRIPQPSHPLKSFNWVKLNEERVSGTVWNEIDDSQVFRILDLEDFEKMFSAYQRHQACMQEGPQRERGNVRDGGAASRPLPAVEASAHRTEKASRSMVSATGAKKELGSTEDIYITSRKVKELSVIDGRRAQNCIILLSKLKLSNDEIRQAILRMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARADRFLYEMSRIDHYQQRLQALFFKKKFQERLAEAKPKVEAILLASRELTLSQRLKQMLEVVLAIGNFMNKGQRGGAYGFRVASLNKIADTKSSIDRNISLLHYLIMILEKHFPDILNMPSELKHLSEAAKVNLAELEKEVSILRRGLRAVEVELEYQRHQARDPNDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKALTHFGEQESKMQPDEFFGIFDTFLQAFLEARQDLEAMRRRKEEDERRARMEFMLKEQREKERWQRQRKVLAGGALEESGEFDDLVSALRSGEVFDKDLSKFKRNRKRPGSQVPEVTRERAINRLNY
Tissue specificity：In early embryogenesis, expression is confined to embryonic ectoderm. Highly dynamic expression in later stages of gastrulation. In early somite stages, detected in posterior node and persists until 9-10 somites have developed when expression is concentrated in the chordoneural hinge. During organogenesis, expressed in the CNS, PNS, liver primordia, limb buds and genital tubercle. {ECO:0000269|PubMed:15464228, ECO:0000269|PubMed:15533824}.
Induction：
Developmental stage：Expressed in the embryonic myocardium: not expressed in the myocardium at 9.5 dpc but is present in epicardial cells. At 10.5 dpc, expressed in the mesenchyme surrounding the ventral foregut and in regions enriched in cardiac progenitors, as well as the epicardium and lining of the pericardial cavity. By 12.5 dpc, expressed throughout the myocardium and ventricular trabeculae. {ECO:0000269|PubMed:26526197}.
Protein families：Formin homology family