GTR1_MOUSE P17809
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UniProt:P17809
Recommended name:Solute carrier family 2, facilitated glucose transporter member 1
EC number:
Alternative names:(Glucose transporter type 1, erythrocyte/brain) (GLUT-1) (GT1)
Cleaved into:
GeneID:20525
Gene names (primary ):Slc2a1
Gene names (synonym ):Glut1
Gene names (ORF ):
Length:492
Mass:53985
Sequence:MDPSSKKVTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWNHRYGEPIPSTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVAAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEEGRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLERLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
Tissue specificity:Retina (at protein level). {ECO:0000269|PubMed:25957687}.
Induction:
Developmental stage:Levels decline 3-fold between days 7.5 and 12.5 of gestation. At 7.5 dpc, expressed more strongly in extraembryonic tissues than in the embryo proper. Expressed in amnion, chorion, and ectoplacental cone. In the yolk sac, expressed more strongly in the mesoderm layer than the ectoderm. Expression fairly widespread in the embryo at 8.5 dpc, but by 10.5 dpc, expression is down-regulated and observed in the eye and the spinal cord. {ECO:0000269|PubMed:1289053, ECO:0000269|PubMed:1765007}.
Protein families:Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily