EMIL3_MOUSE   P59900


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UniProt:P59900

Recommended name:EMILIN-3

EC number:

Alternative names:(EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5) (Elastin microfibril interface-located protein 3) (Elastin microfibril interfacer 3)

Cleaved into:

GeneID:280635

Gene names  (primary ):Emilin3

Gene names  (synonym ):Emilin5

Gene names  (ORF ):

Length:758

Mass:82396

Sequence:MGRRLSVWLCTVAALLSGAQAKGTPLLARPAQPSASRYSLYTTGWRPRLRPGPHKSLCAYVVHRNVTCVLQEGAESYIKAEYRNCGWGPNCPSTVRYRTVFRPRYKIGYKTVTDLAWRCCPGLTGESCPEHLTDHGATPPHQEPEPQIPLGQLGPGPRPSPYSREAPRPRGRKGQGPFGERLEQRLSQAYGTLSGLVASHENPNRITGDSRAPVVPIGFGVIPEGLVAPEDRGRGPLIPPLSEILSKVTEVSNTLQTKVQLLDEVRGLALGHEAHLQRLREAPPSPLTSLALLEEYVDQRLQRLWGSLLDGFEQKLQGVQSECDLRVQEVRQQCEEGQAASQRLHQSLDGRELALRRELSQLGTQLQGLTLTGGGTCCSQLALISARVDSLERNLQAVTETQGGPGTLAADELARLSAAMLQGGVDGLLEGLETINGTENGARGCCLRMEVGGWGVGGFGSTLEQRVQSLEERLATLTGELSPESAIPDRSARPLVHSELAVLEQRLVSLETSCTPSTTTAILDNLVAEVKAWQSRSEALLHQVARHTALLQQLNGTVAEVQGQLAEGTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFSAANTSLDERERRVEAEVHTIQEQISSQGSRLQAGHRQVLNLRGELEQLKAGMANVARGLSRCRDTAQELQHTVGHFDQRVAQVEGACERLGLLATHLNSLPTEQLRSREGLWGHIDKLNHTLAQHTQDIARLRDDLLDCRAQLAEVRPGRAD

Tissue specificity:

Induction:

Developmental stage:At 9.5 dpc, expression is only observed in the tailbud and the hindgut. At 11.5 dpc the expression is found at sites of bone formation, i.e. surrounding mesenchymal condensates in the fore- and hindlimbs, the nose, the maxilla, and the other parts of the jaw. At 13.5 dpc, detected in perichondrium and around developing skeletons, but barely detectable in mature osteoblasts. At 14.5 dpc it is strongly expressed in the enteric nerves of the digestive tract and the bladder. Expression is also observed surrounding the main branches of the alveoli and surrounding sites of bone formation in skull and trunk. {ECO:0000269|PubMed:12221002, ECO:0000269|PubMed:14706625}.

Protein families:


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