NKX61_MOUSE Q99MA9
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UniProt:Q99MA9
Recommended name：Homeobox protein Nkx-6.1
EC number：
Alternative names：(Homeobox protein NK-6 homolog A)
Cleaved into：
GeneID：18096
Gene names (primary )：Nkx6-1
Gene names (synonym )：Nkx6.1 Nkx6a
Gene names (ORF )：
Length：365
Mass：37705
Sequence：MLAVGAMEGPRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPTGPPSSSSSSSSSSSPSPPLGSHNPGGLKPPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGTSENEEDDDDYNKPLDPNSDDEKITQLLKKHKSSGGSLLLHASEAEGSS
Tissue specificity：Expressed by neuronal progenitor cells in discrete domains of the ventral neural tube (PubMed:10830170). In the pancreas, expressed exclusively in insulin-producing beta cells of the islets of Langerhans (at protein level) (PubMed:11076772). {ECO:0000269|PubMed:10830170, ECO:0000269|PubMed:11076772}.
Induction：
Developmental stage：In the developing pancreas, detected as early as 10.5 dpc in the majority of epithelial cells. This broad expression pattern persists through 12.5 dpc. Around 13.5 dpc, with the start of the secondary transition, becomes restricted and by 15.5 dpc, exclusively detected in insulin-expressing beta cells and in some scattered ductal and periductal cells (at protein level). {ECO:0000269|PubMed:11076772}.
Protein families：