ACSL4_MOUSE Q9QUJ7
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UniProt:Q9QUJ7
Recommended name:Long-chain-fatty-acid--CoA ligase 4
EC number:EC 6.2.1.3
Alternative names:(Arachidonate--CoA ligase) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4)
Cleaved into:
GeneID:50790
Gene names (primary ):Acsl4
Gene names (synonym ):Acs4 Facl4
Gene names (ORF ):
Length:711
Mass:79077
Sequence:MNLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVAKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWINYLEVNCRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGREAVVHGLNESEASYLITSVELLESKLKAALVDINCVKHIIYVDNKTINRAEYPEGLEIHSMQSVEELGAKPENLSVPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYVQKTLFKIGYDYKLEQIKKGYDAPLCNLILFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTVHDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYCVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKKLTLLAQQKGVEGSWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELKNHYLKDIERMYGGK
Tissue specificity:Abundant in steroidogenic tissues, also found in the kidney, brain and liver.
Induction:Induced by adrenocorticotropic hormone (ACTH) and suppressed by glucocorticoid.
Developmental stage:
Protein families:ATP-dependent AMP-binding enzyme family