TWST2_MOUSE Q9D030
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UniProt:Q9D030
Recommended name:Twist-related protein 2
EC number:
Alternative names:(Dermis-expressed protein 1) (Dermo-1)
Cleaved into:
GeneID:13345
Gene names (primary ):Twist2
Gene names (synonym ):Dermo1
Gene names (ORF ):
Length:160
Mass:18140
Sequence:MEEGSSSPVSPVDSLGTSEEELERQPKRFGRKRRYSKKSSEDGSPTPGKRGKKGSPSAQSFEELQSQRILANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHERLSYAYSVWRMEGAWSMSASH
Tissue specificity:Expressed at low levels in sclerotome and dermatome of somites, and in limb buds at 10.5 dpc. Accumulates predominantly in dermatome, prevertebrae and derivatives of branchial arches by 13 dpc. Also expressed near surface of embryo and in chondrogenic cells. In adult, expressed at low levels in skin, bladder, uterus, aorta and heart. {ECO:0000269|PubMed:7589808}.
Induction:By TNF-alpha. {ECO:0000269|PubMed:12553906}.
Developmental stage:In the embryo, expression is detected at 10.5 dpc, increases continuously through to 17.5 dpc and is also high in neonates. Down-regulated in adults. {ECO:0000269|PubMed:7589808}.
Protein families: