LFNG_MOUSE O09010
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UniProt:O09010
Recommended name：Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
EC number：EC 2.4.1.222
Alternative names：(O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)
Cleaved into：
GeneID：16848
Gene names (primary )：Lfng
Gene names (synonym )：
Gene names (ORF )：
Length：378
Mass：41952
Sequence：MLQRCGRRLLLALVGALLACLLVLTADPPPTPMPAERGRRALRSLAGSSGGAPASGSRAAVDPGVLTREVHSLSEYFSLLTRARRDADPPPGVASRQGDGHPRPPAEVLSPRDVFIAVKTTRKFHRARLDLLFETWISRHKEMTFIFTDGEDEALAKLTGNVVLTNCSSAHSRQALSCKMAVEYDRFIESGKKWFCHVDDDNYVNLRALLRLLASYPHTQDVYIGKPSLDRPIQATERISEHKVRPVHFWFATGGAGFCISRGLALKMGPWASGGHFMSTAERIRLPDDCTIGYIVEALLGVPLIRSGLFHSHLENLQQVPTTELHEQVTLSYGMFENKRNAVHIKGPFSVEADPSRFRSVHCHLYPDTPWCPRSAIF
Tissue specificity：Detected at 12.5 dpc in all tissues examined with the highest level observed in adult brain and spleen. Detected in the dental epithelium.
Induction：
Developmental stage：Developmental protein. During segmentation it shows a cyclic transcription pattern which is under the control of Notch. Expressed in the caudal region of the presomitic mesoderm with each cycle corresponding to the formation time of one somite. In the dental epithelium it is detected at stage 13.5 dpc. The pattern of expression corresponds exactly to the formation of the enamel knot between late bud and early cap stages. {ECO:0000269|PubMed:10341080, ECO:0000269|PubMed:12110168, ECO:0000269|PubMed:12110169, ECO:0000269|PubMed:9690473}.
Protein families：Glycosyltransferase 31 family