OTP_MOUSE O09113
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UniProt:O09113
Recommended name:Homeobox protein orthopedia
EC number:
Alternative names:
Cleaved into:
GeneID:18420
Gene names (primary ):Otp
Gene names (synonym ):
Gene names (ORF ):
Length:325
Mass:34159
Sequence:MLSHADLLDARLGMKDAAELLGHREAVKCRLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAGLQSHLYQPAFPGMVPASLPGPSNVSGSPQLCSSPDSSDVWRGTSIASLRRKALEHTVSMSFT
Tissue specificity:Restricted regions of the developing forebrain, hindbrain, and spinal cord. {ECO:0000269|PubMed:7913821}.
Induction:
Developmental stage:First detected at 9.5 dpc in restricted domains of the developing diencephalon and along all the hindbrain and the spinal cord. At 10 dpc, found in the medioventral region of the developing spinal cord. At 12.5 dpc, expressed in restricted zones in the preoptic, postoptic and dorsoposterior regions. At later stages, in the intermedial region of the lateral horn, in the optic tract, the presumptive stria terminalis, the amygdaloid complex of the lateral horn in the spinal cord. {ECO:0000269|PubMed:7913821}.
Protein families:Paired homeobox family, Bicoid subfamily