IKBD_MOUSE   Q2TB02


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UniProt:Q2TB02

Recommended name:NF-kappa-B inhibitor delta

EC number:

Alternative names:(I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS)

Cleaved into:

GeneID:243910

Gene names  (primary ):Nfkbid

Gene names  (synonym ):Ikbns

Gene names  (ORF ):

Length:327

Mass:34942

Sequence:MEDSLDTRLYPEPSLSQVGSWRVSSLPSGSPQLPSPTGPSLETARAHILALGPQQLLAQDEEGDTLLHLFAARGLRWAAYAAAEVLQMYRQLDIREHKGKTPLLVAAAANQPLIVEDLLSLGAEPNATDHQGRSVLHVAATYGLPGVLSAVFKSGIQVDLEARDFEGLTPLHTAVLALNAAMLPASVCPRMQNSQARDRLTCVQMLLQMGASHTSQEIKSNKTILHLAVQAANPTLVQLLLGLPRGDLRAFVNMKAHGNTALHMAAALPPGPPQEAIVRHLLAAGADPTLRNLENEQPVHLLRPGPGPEGLRQLLKRSRTAPPGLSS

Tissue specificity:Specifically expressed in spleen and at low levels in thymus. Expressed in a population of antigen-presenting dendritic cells which may act as regulators of systemic inflammatory response. {ECO:0000269|PubMed:11931770, ECO:0000269|PubMed:16410444}.

Induction:Up-regulated in thymocytes upon TCR-triggered cell death (at protein level). Up-regulated by IL-10 or LPS. {ECO:0000269|PubMed:11931770, ECO:0000269|PubMed:15749903}.

Developmental stage:

Protein families:NF-kappa-B inhibitor family


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