IKBD_MOUSE Q2TB02
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UniProt:Q2TB02
Recommended name:NF-kappa-B inhibitor delta
EC number:
Alternative names:(I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS)
Cleaved into:
GeneID:243910
Gene names (primary ):Nfkbid
Gene names (synonym ):Ikbns
Gene names (ORF ):
Length:327
Mass:34942
Sequence:MEDSLDTRLYPEPSLSQVGSWRVSSLPSGSPQLPSPTGPSLETARAHILALGPQQLLAQDEEGDTLLHLFAARGLRWAAYAAAEVLQMYRQLDIREHKGKTPLLVAAAANQPLIVEDLLSLGAEPNATDHQGRSVLHVAATYGLPGVLSAVFKSGIQVDLEARDFEGLTPLHTAVLALNAAMLPASVCPRMQNSQARDRLTCVQMLLQMGASHTSQEIKSNKTILHLAVQAANPTLVQLLLGLPRGDLRAFVNMKAHGNTALHMAAALPPGPPQEAIVRHLLAAGADPTLRNLENEQPVHLLRPGPGPEGLRQLLKRSRTAPPGLSS
Tissue specificity:Specifically expressed in spleen and at low levels in thymus. Expressed in a population of antigen-presenting dendritic cells which may act as regulators of systemic inflammatory response. {ECO:0000269|PubMed:11931770, ECO:0000269|PubMed:16410444}.
Induction:Up-regulated in thymocytes upon TCR-triggered cell death (at protein level). Up-regulated by IL-10 or LPS. {ECO:0000269|PubMed:11931770, ECO:0000269|PubMed:15749903}.
Developmental stage:
Protein families:NF-kappa-B inhibitor family