CRY2_MOUSE   Q9R194


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UniProt:Q9R194

Recommended name:Cryptochrome-2

EC number:

Alternative names:

Cleaved into:

GeneID:12953

Gene names  (primary ):Cry2

Gene names  (synonym ):Kiaa0658

Gene names  (ORF ):

Length:592

Mass:66850

Sequence:MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQAGSISNTGPRALSSGPASPKRKLEAAEEPPGEELTKRARVTEMPTQEPASKDS

Tissue specificity:Expression in the retina is restricted to the photoreceptor layer (at protein level) (PubMed:29561690). Expressed in all tissues examined including heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. Weak expression in spleen. {ECO:0000269|PubMed:10521578, ECO:0000269|PubMed:11779462, ECO:0000269|PubMed:24154698, ECO:0000269|PubMed:29561690, ECO:0000269|PubMed:9801304}.

Induction:Shows no clear circadian oscillation pattern in testis, cerebellum nor liver. In skeletal muscle, under constant darkness and 12 hours light:12 hours dark conditions, levels peak between ZT6 and ZT9. {ECO:0000269|PubMed:10428031, ECO:0000269|PubMed:10521578, ECO:0000269|PubMed:19917250}.

Developmental stage:

Protein families:DNA photolyase class-1 family


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