CRY2_MOUSE Q9R194
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UniProt:Q9R194
Recommended name:Cryptochrome-2
EC number:
Alternative names:
Cleaved into:
GeneID:12953
Gene names (primary ):Cry2
Gene names (synonym ):Kiaa0658
Gene names (ORF ):
Length:592
Mass:66850
Sequence:MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQAGSISNTGPRALSSGPASPKRKLEAAEEPPGEELTKRARVTEMPTQEPASKDS
Tissue specificity:Expression in the retina is restricted to the photoreceptor layer (at protein level) (PubMed:29561690). Expressed in all tissues examined including heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. Weak expression in spleen. {ECO:0000269|PubMed:10521578, ECO:0000269|PubMed:11779462, ECO:0000269|PubMed:24154698, ECO:0000269|PubMed:29561690, ECO:0000269|PubMed:9801304}.
Induction:Shows no clear circadian oscillation pattern in testis, cerebellum nor liver. In skeletal muscle, under constant darkness and 12 hours light:12 hours dark conditions, levels peak between ZT6 and ZT9. {ECO:0000269|PubMed:10428031, ECO:0000269|PubMed:10521578, ECO:0000269|PubMed:19917250}.
Developmental stage:
Protein families:DNA photolyase class-1 family