NTRK1_MOUSE   Q3UFB7


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UniProt:Q3UFB7

Recommended name:High affinity nerve growth factor receptor

EC number:EC 2.7.10.1

Alternative names:(Neurotrophic tyrosine kinase receptor type 1)

Cleaved into:

GeneID:18211

Gene names  (primary ):Ntrk1

Gene names  (synonym ):

Gene names  (ORF ):

Length:799

Mass:87738

Sequence:MLRGQRLGQLGWHRPAAGLGSLMTSLMLACASAASCREVCCPVGPSGLRCTRAGSLDTLRGLRGAGNLTELYVENQQHLQRLEFEDLQGLGELRSLTIVKSGLRFVAPDAFRFTPRLSHLNLSSNALESLSWKTVQGLSLQDLTLSGNPLHCSCALFWLQRWEQEGLCGVHTQTLHDSGPGDQFLPLGHNTSCGVPTVKIQMPNDSVEVGDDVFLQCQVEGLALQQADWILTELEGAATVKKFGDLPSLGLILVNVTSDLNKKNVTCWAENDVGRAEVSVQVSVSFPASVHLGLAVEQHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTQFLESALTNETMRHGCLRLNQPTHVNNGNYTLLAANPYGQAAASVMAAFMDNPFEFNPEDPIPVSFSPVDGNSTSRDPVEKKDETPFGVSVAVGLAVSAALFLSALLLVLNKCGQRSKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSYLDVLG

Tissue specificity:

Induction:Expression oscillates in a circadian manner in the suprachiasmatic nucleus (SCN) of the brain. {ECO:0000269|PubMed:23785138}.

Developmental stage:First detected at 13.5 dpc, a time coinciding with the requirement of sympathetic neurons for NGF. {ECO:0000269|PubMed:8815902}.

Protein families:Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily


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