NTRK1_MOUSE Q3UFB7
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UniProt:Q3UFB7
Recommended name:High affinity nerve growth factor receptor
EC number:EC 2.7.10.1
Alternative names:(Neurotrophic tyrosine kinase receptor type 1)
Cleaved into:
GeneID:18211
Gene names (primary ):Ntrk1
Gene names (synonym ):
Gene names (ORF ):
Length:799
Mass:87738
Sequence:MLRGQRLGQLGWHRPAAGLGSLMTSLMLACASAASCREVCCPVGPSGLRCTRAGSLDTLRGLRGAGNLTELYVENQQHLQRLEFEDLQGLGELRSLTIVKSGLRFVAPDAFRFTPRLSHLNLSSNALESLSWKTVQGLSLQDLTLSGNPLHCSCALFWLQRWEQEGLCGVHTQTLHDSGPGDQFLPLGHNTSCGVPTVKIQMPNDSVEVGDDVFLQCQVEGLALQQADWILTELEGAATVKKFGDLPSLGLILVNVTSDLNKKNVTCWAENDVGRAEVSVQVSVSFPASVHLGLAVEQHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTQFLESALTNETMRHGCLRLNQPTHVNNGNYTLLAANPYGQAAASVMAAFMDNPFEFNPEDPIPVSFSPVDGNSTSRDPVEKKDETPFGVSVAVGLAVSAALFLSALLLVLNKCGQRSKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIMENPQYFSDTCVHHIKRQDIILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASENARQDFQREAELLTMLQHQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIECITQGRELERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQALAQAPPSYLDVLG
Tissue specificity:
Induction:Expression oscillates in a circadian manner in the suprachiasmatic nucleus (SCN) of the brain. {ECO:0000269|PubMed:23785138}.
Developmental stage:First detected at 13.5 dpc, a time coinciding with the requirement of sympathetic neurons for NGF. {ECO:0000269|PubMed:8815902}.
Protein families:Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily