GOLI_MOUSE   Q8VEM1


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UniProt:Q8VEM1

Recommended name:E3 ubiquitin-protein ligase RNF130

EC number:EC 2.3.2.27

Alternative names:(G1-related zinc finger protein) (Goliath homolog) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130)

Cleaved into:

GeneID:59044

Gene names  (primary ):Rnf130

Gene names  (synonym ):G1rp

Gene names  (ORF ):

Length:419

Mass:46376

Sequence:MSGAARAGPARLAALALLTCSLWPTRADNASQEYYTALINVTVQEPGRGTPLTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRAALGDLAGDSSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF

Tissue specificity:Expression is highest in liver, with lesser amounts in the lung, spleen, brain, heart, kidney and testis. {ECO:0000269|PubMed:10806348}.

Induction:Up-regulated in response to interleukin-3 (IL-3) withdrawal-induced apoptosis of 32Dcl3 cells (derived from bone marrow). {ECO:0000269|PubMed:10806348}.

Developmental stage:

Protein families:


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