GOLI_MOUSE Q8VEM1
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UniProt:Q8VEM1
Recommended name:E3 ubiquitin-protein ligase RNF130
EC number:EC 2.3.2.27
Alternative names:(G1-related zinc finger protein) (Goliath homolog) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130)
Cleaved into:
GeneID:59044
Gene names (primary ):Rnf130
Gene names (synonym ):G1rp
Gene names (ORF ):
Length:419
Mass:46376
Sequence:MSGAARAGPARLAALALLTCSLWPTRADNASQEYYTALINVTVQEPGRGTPLTFRIDRGRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQAVNRRAALGDLAGDSSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLCYMIIRATASLNANEVEWF
Tissue specificity:Expression is highest in liver, with lesser amounts in the lung, spleen, brain, heart, kidney and testis. {ECO:0000269|PubMed:10806348}.
Induction:Up-regulated in response to interleukin-3 (IL-3) withdrawal-induced apoptosis of 32Dcl3 cells (derived from bone marrow). {ECO:0000269|PubMed:10806348}.
Developmental stage:
Protein families: