IFT81_MOUSE O35594
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UniProt:O35594
Recommended name：Intraflagellar transport protein 81 homolog
EC number：
Alternative names：(Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1)
Cleaved into：
GeneID：12589
Gene names (primary )：Ift81
Gene names (synonym )：Cdv-1 Cdv1
Gene names (ORF )：
Length：676
Mass：79285
Sequence：MSDQIKFIVDSLNKEPFKKNYNLITFDSLGPMQLLQVLNDVLAEIDPKQDVDIREEMPEQTAKRMLNLLGILKYKPPGNATDMSTFRQGLVIGSKPVIYPVLHWLLQRSNELKKRAYLARFLIKLEVPSEFLQDETVADTNKQYEELMEAFKTLHKECEQLKTSGFSTAEIRRDISAMEEEKDQLMKRVERLKKRVETVQNHQRMLKIARQLRVEKEREEFLAQQKQEQKNQLFHAVQRLQRVQNQLKSMRHAAADAKPESLMKRLEEEIKFNSYMVTEKFPKELESKKKELHFLQKVVSEPAMGHSDLLELETKVNEVNTEINQLIEKKMMRNEPIEGKLSLYRQQASIISRKKEAKAEELQETKEKLASLEREVLVKTNQTREFDGTEVLKGDEFKRYVSKLRSKSTVFKKKHQIIAEFKAEFGLLQRTEELLKQRQETIQHQLRTIEEKKGISGYSYTQEELERVSALKSEVDEMKGRTLDDMSEMVKKLNSLVSEKKSALAPVIKELRQLRQKCQELTQECDEKKAQYDSCAAGLESNRSKLEQEVRGLREECLQEESKYHYTNCMIKNLEVELRRATDEMKAYVSSDQQEKRKAIREQYTKNITEQENLGKKLREKQKAVRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSPASIGQVIQEGGEDRLVL
Tissue specificity：Isoform CDV-1 is expressed specifically in heart and suppressed specifically in ventricles, but not in auricles, of carnitine-deficient juvenile visceral steatosis (JVS) mice. Isoform CDV-1R is expressed predominantly in the testis. Co-localizes with RABL2/RABL2A in the midpiece of elongated spermatids within the testis (at protein level). {ECO:0000269|PubMed:12549821, ECO:0000269|PubMed:23055941, ECO:0000269|PubMed:9187371}.
Induction：
Developmental stage：Isoform CDV-1R is poorly expressed in the testis 15 days after birth. Levels increase sharply between days 15 and 30 reaching a maximum by day 45 and the onset of spermatogenesis. {ECO:0000269|PubMed:12549821}.
Protein families：IFT81 family