MYOG_MOUSE   P12979


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UniProt:P12979

Recommended name:Myogenin

EC number:

Alternative names:(MYOD1-related protein)

Cleaved into:

GeneID:17928

Gene names  (primary ):Myog

Gene names  (synonym ):

Gene names  (ORF ):

Length:224

Mass:25203

Sequence:MELYETSPYFYQEPHFYDGENYLPVHLQGFEPPGYERTELSLSPEARGPLEEKGLGTPEHCPGQCLPWACKVCKRKSVSVDRRRAATLREKRRLKKVNEAFEALKRSTLLNPNQRLPKVEILRSAIQYIERLQALLSSLNQEERDLRYRGGGGPQPMVPSECNSHSASCSPEWGNALEFGPNPGDHLLAADPTDAHNLHSLTSIVDSITVEDMSVAFPDETMPN

Tissue specificity:Expressed in myoblast cells. Expressed weakly in myotubes (at protein level). Expressed strongly in denervated muscles and in satellite cells isolated from denervated muscles. Expressed weakly in innervated muscle and in satellite cells isolated from innervated muscles. {ECO:0000269|PubMed:21465538, ECO:0000269|PubMed:21798092}.

Induction:Up-regulated in denervated muscles (at protein level). Up-regulated during myogenesis in the embryo and in cell culture models of myogenic differentiation via the p38 MAPK signaling pathway. {ECO:0000269|PubMed:21465538, ECO:0000269|PubMed:21798092, ECO:0000269|PubMed:22847234}.

Developmental stage:Expressed in the myotome of the somites at 8.5 dpc, onward (at protein level). Expressed in proximal region of both the hindlimb and the forelimb at 11.5 dpc, onward. Expressed during muscle maturation between 15 and 17 dpc and decreases thereafter. Not detected within the heart. {ECO:0000269|PubMed:1705035, ECO:0000269|PubMed:2552320, ECO:0000269|PubMed:7929574}.

Protein families:


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