AK1A1_MOUSE Q9JII6
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UniProt:Q9JII6
Recommended name:Aldo-keto reductase family 1 member A1
EC number:EC 1.1.1.2
Alternative names:(Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (Glucuronolactone reductase) (EC 1.1.1.20)
Cleaved into:
GeneID:58810
Gene names (primary ):Akr1a1
Gene names (synonym ):Akr1a4
Gene names (ORF ):
Length:325
Mass:36587
Sequence:MTASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLYPFNDPY
Tissue specificity:Widely expressed. {ECO:0000269|PubMed:10842086, ECO:0000269|PubMed:15769935}.
Induction:Fear memory increases expression 7-fold. {ECO:0000269|PubMed:11533224}.
Developmental stage:Detected at high levels in several tissues including neural ectoderm, gut endoderm, somites, branchial arches, otic vesicles, limb buds and tail bud. {ECO:0000269|PubMed:10842086}.
Protein families:Aldo/keto reductase family