AK1A1_MOUSE   Q9JII6


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UniProt:Q9JII6

Recommended name:Aldo-keto reductase family 1 member A1

EC number:EC 1.1.1.2

Alternative names:(Alcohol dehydrogenase [NADP(+)]) (Aldehyde reductase) (Glucuronate reductase) (Glucuronolactone reductase) (EC 1.1.1.20)

Cleaved into:

GeneID:58810

Gene names  (primary ):Akr1a1

Gene names  (synonym ):Akr1a4

Gene names  (ORF ):

Length:325

Mass:36587

Sequence:MTASSVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALNKNWRYIVPMITVDGKRVPRDAGHPLYPFNDPY

Tissue specificity:Widely expressed. {ECO:0000269|PubMed:10842086, ECO:0000269|PubMed:15769935}.

Induction:Fear memory increases expression 7-fold. {ECO:0000269|PubMed:11533224}.

Developmental stage:Detected at high levels in several tissues including neural ectoderm, gut endoderm, somites, branchial arches, otic vesicles, limb buds and tail bud. {ECO:0000269|PubMed:10842086}.

Protein families:Aldo/keto reductase family


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