SMOC1_MOUSE   Q8BLY1


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UniProt:Q8BLY1

Recommended name:SPARC-related modular calcium-binding protein 1

EC number:

Alternative names:(SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1)

Cleaved into:

GeneID:64075

Gene names  (primary ):Smoc1

Gene names  (synonym ):Srg

Gene names  (ORF ):

Length:463

Mass:51076

Sequence:MLPARVRLLTPHLLLVLVQLSPAGGHRTTGPRFLISDRDPPCNPHCPRTQPKPICASDGRSYESMCEYQRAKCRDPALAVVHRGRCKDAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGPVTDKPLSQGNSGRKVSFRFFLTLNSDDGSKPTPTMETQPVFDGDEITAPTLWIKHLVIKDSKLNNTNVRNSEKVHSCDQERQSALEEARQNPREGIVIPECAPGGLYKPVQCHQSTGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKSVEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVAHWYFSQLDSNSSDDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEGGSLGSFPQGKRAGTNPFIGRLV

Tissue specificity:Widely expressed in many tissues with a strongest signal in ovary.

Induction:

Developmental stage:Found in the forebrain, midbrain, hindbrain, pharyngeal arch, somites, and forelimb buds at day 9.5 dpc. At day 10.5 dpc, strongly expressed in dorsal neural tube, developing pharyngeal arches and frontonasal region with low expression in the ectoderm overlying the developing optic vesicle, expression can be observed in the optic stalk. At 11.5 dpc it is localized to the closure site of the optic cup. In developing limbs between days 10.5 dpc and 11.5 dpc, it is found in both dorsal and ventral regions, but expression is predominant dorsal in hindlimb bud and not detected in the most anterior, posterior, and distal parts of limb buds. Expression coinciding with chondrogenic condensation can be observed at 12.5 dpc. Expression is restricted to future synovial joint regions at day 13.5 dpc. {ECO:0000269|PubMed:21194678, ECO:0000269|PubMed:21750680}.

Protein families:


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