PDK2_MOUSE Q9JK42
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UniProt:Q9JK42
Recommended name:[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
EC number:EC 2.7.11.2
Alternative names:[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2)
Cleaved into:
GeneID:18604
Gene names (primary ):Pdk2
Gene names (synonym ):
Gene names (ORF ):
Length:407
Mass:46041
Sequence:MRWVRALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVRLANIMKEINLLPDRVLGTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNATNANQPIHMVYVPSHLYHMLFELFKNAMRATVESHESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
Tissue specificity:Detected in heart (at protein level). {ECO:0000269|PubMed:21190881}.
Induction:Up-regulated by glucose and palmitic acid. Up-regulated by PPARD. {ECO:0000269|PubMed:16631612, ECO:0000269|PubMed:17669420}.
Developmental stage:
Protein families:PDK/BCKDK protein kinase family