U2AF4_MOUSE Q8BGJ9
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q8BGJ9
Recommended name：Splicing factor U2AF 26 kDa subunit
EC number：
Alternative names：(U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2AF1-like 4)
Cleaved into：
GeneID：233073
Gene names (primary )：U2af1l4
Gene names (synonym )：U2af26
Gene names (ORF )：
Length：220
Mass：25836
Sequence：MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIVLLNLYRNPQNTAQTADGSHCHVSDVEVQEHYDNFFEEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDAERAVAELNNRWFNGQAVHAELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISRNLRRQLYGRGPRHRSPPRSHTGHRPRERNRRRSPDHRHGRF
Tissue specificity：Ubiquitous. Highly expressed in the brain. {ECO:0000269|PubMed:11739736}.
Induction：Up-regulated in response to T-cell activation (at protein level) (PubMed:16819553). Circadian alternative splicing switch accounts for rhythmic isoform expression. A circadian splicing switch produces isoform 3 in the brain cerebellum and liver (at protein level). Isoform 3 expression is regulated with the circadian rhythm but is also quickly increased upon light exposure (4-8 hours after light exposure). Expression of isoform 3 changes approximately 5-fold across a period of 24 hours, with concomitant changes in isoform 1, resulting in total U2af1l4 remaining constant (PubMed:24837677). {ECO:0000269|PubMed:16819553, ECO:0000269|PubMed:24837677}.
Developmental stage：
Protein families：Splicing factor SR family