CPEB3_MOUSE Q7TN99
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UniProt:Q7TN99
Recommended name：Cytoplasmic polyadenylation element-binding protein 3
EC number：
Alternative names：(CPE-BP3) (CPE-binding protein 3) (mCPEB-3)
Cleaved into：
GeneID：208922
Gene names (primary )：Cpeb3
Gene names (synonym )：Kiaa0940
Gene names (ORF )：
Length：716
Mass：78335
Sequence：MQDDLLMDKSKTQPQSQQQQRQQQQQQQQLQPEPGAAEAPSTPLSSEIPKPEDSSAVPALSPASAPPAPNGPDKMQMESPLLPGLSFHQPPQQPPPPQEPTAPGASLSPSFGSTWSTGTTNAVEDSFFQGITPVNGTMLFQNFPHHVNPVFGGTFSPQIGLAQTQHHQQPPPPAPQPPQPAQPPQAQPSQQRRSPASPSQAPYAQRSAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSNPWGGLQAGRDPRRAVGVGVGVGVGVPSPLNPISPLKKPFSSNVIAPPKFPRAAPLTSKSWMEDNAFRTDNGNNLLPFQDRSRPYDTFNLHSLENSLMDMIRTDHEPLKGKHYPNSGPPMSFADIMWRNHFAGRMGINFHHPGTDNIMALNTRSYGRRRGRSSLFPFEDAFLDDSHGDQALSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHNDIDKRVEVKPYVLDDQMCDECQGTRCGGKFAPFFCANVTCLQYYCEYCWASIHSRAGREFHKPLVKEGGDRPRHVPFRWS
Tissue specificity：Highly expressed in brain (at protein level) (PubMed:17024188). In brain, expressed in the hippocampus, granule cells and interneurons of the cerebellum, and mitral cells of the olfactory bulb (at protein level) (PubMed:17024188). Detected in the spinal cord and in peripheral dorsal root ganglia (at protein level) (PubMed:26915043). In the retina, strongly expressed in the retinal ganglion layer and, to a lesser extent, in the inner margin of the inner nuclear layer with expression also detected in the inner and outer plexiform layers (at protein level) (PubMed:20003455). Highly expressed in brain and heart, less in liver, kidney, embryo, skeletal muscle, lung and ovary (PubMed:12871996). Weakly expressed in granular cells of dentate gyrus and the pyramidal cells of CA3 and CA1 of the hippocampus (PubMed:12871996). {ECO:0000269|PubMed:12871996, ECO:0000269|PubMed:17024188, ECO:0000269|PubMed:20003455, ECO:0000269|PubMed:26915043}.
Induction：Up-regulated following synaptic activity (at protein level) (PubMed:26074003, PubMed:26074072). Up-regulated in granular cells of the dentate gyrus and the pyramidal cells of CA1 and CA3 after kainate-induced seizures (PubMed:12871996). {ECO:0000269|PubMed:12871996, ECO:0000269|PubMed:26074003, ECO:0000269|PubMed:26074072}.
Developmental stage：In the retina, expression increases throughout postnatal development and remains high in the adult (at protein level). {ECO:0000269|PubMed:20003455}.
Protein families：RRM CPEB family