Summary
| Production Name | ACVR1B Rabbit Monoclonal Antibody |
| Description | Recombinant rabbit monoclonal antibody |
| Host | Rabbit |
| Application | WB,IHC,ICC/IF,ICC |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG |
| Clonality | Monoclonal |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | ACVR1B |
| Alternative Names | ACTR-IB; ACV1B ACVR1B ACVRLK4; SKR2;;ACVR1B |
| Gene ID | |
| SwissProt ID | P36896 |
Application
| Dilution Ratio | WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200 |
| Molecular Weight | Calculated MW: 57 kDa ; Observed MW: 52 kDa |
Background
Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor type-2 (ACVR2A or ACVR2B). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating a many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis.
Research Area