Summary
Performance
Immunogen
Application
Background
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
Research Area
Signal Transduction; Signaling Pathway; Calcium Signaling; Calpain; Cell Biology; Proteolysis / Ubiquitin; Proteolytic enzymes; Cysteine protease; Calpains; Cancer; Cancer Metabolism; Response to hypoxia; Metabolism; Pathways and Processes; Metabolism processes; Hypoxia
