Name: Cleaved N-terminal GSDMD Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe21098
Price: 98 USD
Availability: InStock

Cleaved N-terminal GSDMD Rabbit Monoclonal Antibody

Cat. No.: AMRe21098

Size:20μL Price:$98
Size:50μL Price:$128
Size:100μL Price:$230
Application:WB,ELISA
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:GSDMD

Category: Recombinant Monoclonal Antibodies Tags: Rabbit, Unconjugated, WB, IF, IP, ELISA, Human, Mouse, Rat

Datasheet

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Summary

Production Name	Cleaved N-terminal GSDMD Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,ELISA
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG,Kappa
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%protective protein
Purification	Protein A

Immunogen

Gene Name	GSDMD
Alternative Names	FKSG10, gasdermin D, Gasdermin domain-containing protein 1, gasderminD, Gasdermin-D
Gene ID	79792
SwissProt ID	P57764

Application

Dilution Ratio	WB 1:2000-1:10000,ELISA 1:5000-1:20000
Molecular Weight	Calculated MW:53kD;Observed MW:35kD

Background

Cell localization:[Gasdermin-D]: Cytoplasm, cytosol . Inflammasome . In response to a canonical inflammasome stimulus, such as nigericin, recruited to NLRP3 inflammasone with similar kinetics to that of uncleaved CASP1 precursor. .; [Gasdermin-D, N-terminal]: Cell membrane ; Multi-pass membrane protein . Secreted . Released in the extracellular milieu following pyroptosis. .; [Gasdermin-D, C-terminal]: Cytoplasm, cytosol ..

Research Area

Neutrophil extracellular trap formation