Name: GSDMD Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe87750
Price: 168 USD
Availability: InStock

GSDMD Rabbit Monoclonal Antibody

Cat: AMRe87750

Size:20μL Price:$98
Size:50μL Price:$168
Size:100μL Price:$300
Application:WB,IHC,FC,IP
Reactivity:Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:GSDMD Category: Recombinant Monoclonal Antibody Tags: Rabbit, Unconjugated, WB, IHC-P, FC, IP, Mouse, Rat

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Summary

Production Name	GSDMD Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,IHC,FC,IP
Reactivity	Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.
Purification	Affinity Purification

Immunogen

Gene Name	GSDMD
Alternative Names	DF5L; M2-4; Dfna5l; GsdmD-1; Gsdmdc1; 1810036L03Rik
Gene ID	69146
SwissProt ID	Q9D8T2

Application

Dilution Ratio	WB 1:500-1:2000,IHC 1:200-1:1000,FC 1:200-1:500,IP 1:20-1:50
Molecular Weight	Calculated MW:53 kDa; Observed MW:53,31 kDa

Background

Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D). [provided by Alliance of Genome Resources, Apr 2022]

Research Area