Name: Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody
Brand: Enkilife Limited
SKU: AMRe03054
Price: 158 USD
Availability: InStock
Rating: 5 (1 reviews)

Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody

Cat: AMRe03054

Size:50μL Price:$158
Size:100μL Price:$288
Size:200μL Price:$520
Application:WB,ICC/IF,IP
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:F11R Category: Recombinant Monoclonal Antibody Tags: Unconjugated, Cardiovascular, Rabbit, WB, IF, IP, Human

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Summary

Production Name	Junctional Adhesion Molecule 1 Rabbit Monoclonal Antibody
Description	Recombinant rabbit monoclonal antibody
Host	Rabbit
Application	WB,ICC/IF,IP
Reactivity	Human

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG
Clonality	Monoclonal
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification	Affinity Purification

Immunogen

Gene Name	F11R
Alternative Names	F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321
Gene ID	50848
SwissProt ID	Q9Y624

Application

Dilution Ratio	WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50
Molecular Weight	Calculated MW: 33 kDa; Observed MW: 33 kDa

Background

Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Research Area

Cardiovascular